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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0776
All Species:
28.79
Human Site:
S741
Identified Species:
52.78
UniProt:
O94874
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94874
NP_056138.1
794
89595
S741
L
V
V
K
Q
L
V
S
Q
S
K
K
T
G
Q
Chimpanzee
Pan troglodytes
XP_518643
794
89625
S741
L
V
V
K
Q
L
V
S
Q
S
K
K
T
G
Q
Rhesus Macaque
Macaca mulatta
XP_001100312
793
89480
S741
L
V
V
K
Q
L
V
S
Q
N
K
K
T
G
Q
Dog
Lupus familis
XP_532236
830
93092
S777
L
V
V
K
H
L
V
S
Q
N
K
K
T
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCJ3
793
89502
S740
L
V
V
K
Q
L
V
S
Q
N
K
K
T
G
Q
Rat
Rattus norvegicus
B2GV24
793
89567
S740
L
V
V
K
Q
L
V
S
Q
N
K
K
S
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510895
871
97174
S818
L
V
V
K
Q
L
V
S
Q
N
K
K
A
G
Q
Chicken
Gallus gallus
Q5ZMG1
789
89086
V736
I
K
Y
Q
G
L
V
V
K
Q
L
I
S
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PGY6
793
88661
V741
L
V
V
K
Q
L
V
V
Q
G
H
G
A
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VI55
782
87464
N725
Q
H
I
R
G
S
L
N
E
D
Q
N
A
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17750
735
80983
L683
S
G
K
F
V
S
Q
L
V
A
Q
I
K
D
L
Sea Urchin
Strong. purpuratus
XP_780358
558
62888
T506
E
E
L
F
R
P
L
T
R
N
Y
Q
E
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LX73
804
89055
E738
A
A
I
S
H
L
K
E
K
L
D
E
S
A
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
86
N.A.
90.5
90.6
N.A.
69.6
74.6
N.A.
62.9
N.A.
35.2
N.A.
23.6
35.8
Protein Similarity:
100
99.7
99.6
90.5
N.A.
95.9
96.4
N.A.
81.2
87.7
N.A.
80.2
N.A.
58.3
N.A.
43.9
52.7
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
86.6
N.A.
86.6
13.3
N.A.
53.3
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
40
N.A.
60
N.A.
40
N.A.
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
8
0
0
24
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
8
0
0
8
0
% D
% Glu:
8
8
0
0
0
0
0
8
8
0
0
8
8
8
0
% E
% Phe:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
16
0
0
0
0
8
0
8
0
54
0
% G
% His:
0
8
0
0
16
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
16
0
0
0
0
0
0
0
0
16
0
0
0
% I
% Lys:
0
8
8
62
0
0
8
0
16
0
54
54
8
0
8
% K
% Leu:
62
0
8
0
0
77
16
8
0
8
8
0
0
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
47
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
54
0
8
0
62
8
16
8
0
8
54
% Q
% Arg:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
16
0
54
0
16
0
0
24
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
39
0
0
% T
% Val:
0
62
62
0
8
0
70
16
8
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _